Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 12/20 | 0.49 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19559432 | 1.00 | PDE4A (0.49) | PDE4AFPR2PDE4BPDE4CPDE4D | |
| SCHEMBL16785337 | 0.84 | PDE4A (0.49) | PDE4AFPR2PDE4BPDE4CPDE4D | |
| SCHEMBL19559455 | 0.84 | PDE4A (0.49) | PDE4AFPR2PDE4BPDE4CPDE4D | |
| SCHEMBL20177904 | 0.83 | FPR2 (0.39) | PDE4AFPR2 | |
| SCHEMBL18117705 | 0.81 | FPR1 (0.47) | PDE4AFPR2PDE4BPDE4CPDE4D | |
| SCHEMBL19559435 | 0.81 | FPR1 (0.47) | PDE4AFPR2PDE4BPDE4CPDE4D | |
| SCHEMBL18590580 | 0.80 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DMAOA | |
| SCHEMBL19559407 | 0.80 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DMAOA | |
| SCHEMBL18590506 | 0.79 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL18590497 | 0.79 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092916-A1 | NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE | 宇部興産株式会社 | 2018-05-24 | — | — | WO | disclosed |