Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.45 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.45 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20177600 | 0.81 | MTNR1A (0.48) | KDM1AKDM1BLMNAMEN1KMT2A | |
| SCHEMBL20177918 | 0.81 | HTR2C (0.40) | ALOX12 | |
| SCHEMBL20177607 | 0.79 | KDM1A (0.31) | KDM1A | |
| SCHEMBL20177917 | 0.79 | KDM1A (0.31) | KDM1A | |
| SCHEMBL29739167 | 0.74 | KDM1A (0.58) | KDM1AKDM1BDPP4DGAT1 | |
| SCHEMBL8243578 | 0.74 | KDM1A (0.58) | KDM1AKDM1BDPP4DGAT1 | |
| SCHEMBL20177679 | 0.73 | KDM1A (0.44) | KDM1AKDM1B | |
| SCHEMBL22778088 | 0.71 | KDM1A (0.56) | KDM1AKDM1BDPP4LMNAMEN1 | |
| SCHEMBL30021045 | 0.71 | KDM1A (0.56) | KDM1AKDM1BDPP4LMNAMEN1 | |
| SCHEMBL17997271 | 0.71 | KDM1A (0.55) | KDM1AKDM1BMEN1KMT2ADGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092916-A1 | NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE | 宇部興産株式会社 | 2018-05-24 | — | — | WO | disclosed |