SCHEMBL20177940 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	FPR1	P21462	8/20	0.47

▸	FPR2	P25090	8/20	0.47

▸	REN	P00797	2/20	0.41

▸	SMN1; SMN2	Q16637	2/20	0.41

▸	LMNA	P02545	1/20	0.41

▸	POLB	P06746	1/20	0.41

▸	NAAA	Q02083	2/20	0.39

▸	ASAH1	Q13510	1/20	0.39

▸	GPBAR1	Q8TDU6	1/20	0.38

▸	PKM	P14618	1/20	0.37

▸	HTT	P42858	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL18579062	0.92	KCNQ2 (0.43)	FPR1FPR2POLBNAAAASAH1
SCHEMBL29434414	0.92	KCNQ2 (0.43)	FPR1FPR2POLBNAAAASAH1
SCHEMBL21173988	0.92	KCNQ2 (0.43)	FPR1FPR2POLBNAAAASAH1
SCHEMBL18106649	0.92	KCNQ2 (0.43)	FPR1FPR2POLBNAAAASAH1
SCHEMBL20177941	0.89	FPR1 (0.43)	FPR1FPR2RENSMN1; SMN2LMNA
SCHEMBL20177574	0.87	FPR1 (0.39)	FPR1FPR2SMN1; SMN2LMNAPOLB
SCHEMBL20177900	0.87	FPR2 (0.42)	FPR1FPR2NAAAASAH1
SCHEMBL20177734	0.84	KCNQ2 (0.37)	FPR1FPR2SMN1; SMN2NAAAASAH1
SCHEMBL20177800	0.83	EDNRB (0.38)	SMN1; SMN2NAAAASAH1PKMHTT
SCHEMBL20177684	0.83	FPR2 (0.43)	FPR1FPR2SMN1; SMN2NAAAASAH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2018092916-A1	NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE	宇部興産株式会社	2018-05-24	—	—	WO	disclosed