Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 14/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.38 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20155526 | 1.00 | MGLL (0.54) | MGLLCHRM3MEN1KMT2AMKNK1 | |
| Hydrochloric Acid SCHEMBL20137395 | 0.99 | MGLL (0.53) | MGLLCHRM3MEN1KMT2AMKNK1 | |
| Hydrochloric Acid SCHEMBL29531222 | 0.99 | MGLL (0.53) | MGLLCHRM3MEN1KMT2AMKNK1 | |
| SCHEMBL20150076 | 0.84 | LMNA (0.40) | MGLLCHRM3MEN1KMT2ASLC6A4 | |
| SCHEMBL20155493 | 0.82 | MGLL (0.58) | MGLLCYP2D6ABHD6 | |
| SCHEMBL20137403 | 0.82 | MGLL (0.58) | MGLLCYP2D6ABHD6 | |
| SCHEMBL20178047 | 0.81 | MGLL (0.74) | MGLLCYP2D6ABHD6 | |
| SCHEMBL20137407 | 0.81 | MGLL (0.74) | MGLLCYP2D6ABHD6 | |
| SCHEMBL20155573 | 0.81 | MGLL (0.74) | MGLLCYP2D6ABHD6 | |
| Hydrochloric Acid SCHEMBL20137389 | 0.81 | MGLL (0.50) | MGLLCHRM3MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093946-A1 | MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-05-24 | — | — | WO | disclosed |