SCHEMBL2017810

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21413783	0.88	ELANE (0.67)	ELANEPPARAPPARGCYP1A2CYP3A4
	Dulofibrate SCHEMBL2110601	0.85	PPARA (0.68)	ELANEPPARAPPARGCYP1A2CYP3A4
	SCHEMBL823203	0.83	PPARA (0.70)	ELANEPPARAPPARGCYP1A2CYP3A4
	SCHEMBL4755814	0.82	PPARA (0.58)	ELANEPPARAPPARGCYP1A2CYP3A4
	SCHEMBL3744538	0.82	ELANE (0.59)	ELANEPPARAPPARGCYP1A2CYP3A4
	SCHEMBL4755987	0.81	PPARA (0.72)	ELANEPPARAPPARGCYP1A2CYP3A4
	SCHEMBL4755982	0.80	PPARA (0.70)	ELANEPPARAPPARGCYP1A2CYP3A4
	SCHEMBL15674282	0.80	PPARA (0.65)	ELANEPPARAPPARGCYP1A2CYP3A4
	SCHEMBL10483695	0.79	ELANE (1.00)	ELANEPPARAPPARGCYP1A2CYP3A4
	SCHEMBL2019433	0.79	ELANE (0.55)	ELANEPPARAPPARGCYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.