Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 5/20 | 0.41 |
| ▸ | NOS1 | P29475 | 3/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | ARG1 | P05089 | 1/20 | 0.38 |
| ▸ | ARG2 | P78540 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | BHMT | Q93088 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16446582 | 1.00 | NOS2 (0.41) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL17852377 | 1.00 | NOS2 (0.41) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL17852379 | 0.90 | NOS2 (0.41) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL17840976 | 0.90 | NOS2 (0.41) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL17852276 | 0.82 | NOS2 (0.44) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL28260909 | 0.82 | NOS2 (0.44) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL16446954 | 0.82 | NOS2 (0.44) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL20192745 | 0.81 | ARG1 (0.44) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL20178606 | 0.81 | OTC (0.46) | NOS2NOS1NOS3SLC1A3SLC1A1 | |
| SCHEMBL16446997 | 0.81 | OTC (0.46) | NOS2NOS1NOS3SLC1A3SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981908-B2 | Amino acid derivatives | MEDIMMUNE LIMITED (GB) | 2018-05-29 | — | — | US | disclosed |