Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 6/20 | 0.37 |
| ▸ | TP53 | P04637 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20174668 | 0.82 | ALDH1A1 (0.40) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL20174671 | 0.82 | PDK2 (0.40) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL20179239 | 0.80 | PDK2 (0.34) | KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL20174649 | 0.79 | PDK2 (0.44) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL20174664 | 0.78 | PDK2 (0.44) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL20174645 | 0.74 | KDM4E (0.38) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL20174636 | 0.72 | KDM4E (0.41) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL20174685 | 0.72 | KDM4E (0.36) | SMN1; SMN2KDM4EALDH1A1TP53MAPT | |
| SCHEMBL20174657 | 0.71 | MEN1 (0.38) | KDM4EALDH1A1HPGDMAPTLMNA | |
| SCHEMBL20174651 | 0.71 | MEN1 (0.39) | KDM4EALDH1A1HPGDCYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180141933-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141933-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | CRY1, NR2E3, ERG | NPC1 2492/4885RAB9A 2250/4885SMN1; SMN2 3407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.