SCHEMBL20179364

SCHEMBL20179364

N=C(N)NCCC[C@H](NC(=O)CNC(=O)[C@H](CS)NC(=O)CC[C@H](N)C(=O)O)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ PTGS1 P23219 1/20 0.64
▸ GSTK1 Q9Y2Q3 1/20 0.64
▸ NOD1 Q9Y239 13/20 0.51
▸ FNTA P49354 3/20 0.45
▸ FNTB P49356 3/20 0.45
▸ PGGT1B P53609 1/20 0.45
▸ GLO1 Q04760 1/20 0.44
▸ FOLH1 Q04609 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutathione SCHEMBL16739377 0.90 PTGS1 (0.76) PTGS1GSTK1NOD1FNTAFNTB
Glutathione SCHEMBL16739379 0.90 PTGS1 (0.76) PTGS1GSTK1NOD1FNTAFNTB
SCHEMBL20179354 0.90 PTGS1 (0.65) PTGS1GSTK1NOD1FNTAFNTB
SCHEMBL28050255 0.88 NOD1 (0.59) PTGS1GSTK1NOD1FNTAFNTB
SCHEMBL13585207 0.88 NOD1 (0.59) PTGS1GSTK1NOD1FNTAFNTB
SCHEMBL13585280 0.88 NOD1 (0.59) PTGS1GSTK1NOD1FNTAFNTB
Glutathione SCHEMBL17165667 0.87 PTGS1 (0.74) PTGS1GSTK1NOD1FNTAFNTB
Glutathione SCHEMBL17165670 0.87 PTGS1 (0.74) PTGS1GSTK1NOD1FNTAFNTB
SCHEMBL20179357 0.85 PTGS1 (0.61) PTGS1GSTK1NOD1FNTAFNTB
SCHEMBL20179363 0.84 PTGS1 (0.70) PTGS1GSTK1NOD1FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230165929-A1 TREATMENT OF RESPIRATORY TRACT DISEASES AND INFECTIONS WITH ASCORBIC ACID COMPOSITIONS RENOVION, INC. 2023-06-01 — — US disclosed
US-20190351005-A1 TREATMENT OF RESPIRATORY TRACT DISEASES AND INFECTIONS WITH ASCORBIC ACID COMPOSITIONS RENOVION, INC. 2019-11-21 — — US disclosed
WO-2018094278-A1 TREATMENT OF RESPIRATORY TRACT DISEASES AND INFECTIONS WITH GLUTATHIONE COMPOSITIONS RENOVION, INC. (US) 2018-05-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230165929-A1 TREATMENT OF RESPIRATORY TRACT DISEASES AND INFECTIONS WITH ASCORBIC ACID COMPOSITIONS GPX1, GPX4, GSR PTGS1 194/4885GSTK1 8/4885NOD1 1784/4885
US-20190351005-A1 TREATMENT OF RESPIRATORY TRACT DISEASES AND INFECTIONS WITH ASCORBIC ACID COMPOSITIONS GPX1, GPX4, GSR PTGS1 194/4885GSTK1 8/4885NOD1 1784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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