Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22381452 | 0.82 | XDH (0.65) | XDHMAPTLMNAHSD17B10ALDH1A1 | |
| SCHEMBL22364269 | 0.79 | XDH (0.67) | XDHMAPTLMNAHSD17B10ALDH1A1 | |
| SCHEMBL8941729 | 0.73 | XDH (0.54) | XDHMAPTLMNAHSD17B10KMT2A | |
| SCHEMBL29390286 | 0.73 | XDH (0.54) | XDHMAPTLMNAHSD17B10KMT2A | |
| SCHEMBL24222108 | 0.73 | XDH (0.53) | XDHKMT2ASLC22A12MEN1NPC1 | |
| SCHEMBL20179667 | 0.71 | XDH (0.39) | XDHSMN1; SMN2SLC22A12 | |
| SCHEMBL22364248 | 0.71 | XDH (0.54) | XDHMAPTLMNAHSD17B10ALDH1A1 | |
| SCHEMBL20179600 | 0.71 | XDH (0.73) | XDHMAPTLMNAHSD17B10ALDH1A1 | |
| SCHEMBL22381443 | 0.65 | XDH (0.49) | XDHSLC22A12 | |
| SCHEMBL24222220 | 0.62 | XDH (0.45) | XDHMAPTALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018005192-A9 | COMPOUNDS AND THEIR USE FOR REDUCING URIC ACID LEVELS | ACQUIST LLC (US) | 2018-05-24 | — | — | WO | disclosed |