Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 10/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22381451 | 0.82 | XDH (0.43) | XDHSLC22A12 | |
| SCHEMBL22381450 | 0.80 | XDH (0.43) | XDHSLC22A12ADORA2B | |
| SCHEMBL20179456 | 0.78 | XDH (0.55) | XDHSLC22A12 | |
| SCHEMBL20179446 | 0.71 | XDH (0.62) | XDHSLC22A12SMN1; SMN2 | |
| SCHEMBL22381443 | 0.70 | XDH (0.49) | XDHSLC22A12 | |
| SCHEMBL20179600 | 0.67 | XDH (0.73) | XDHSLC22A12 | |
| SCHEMBL22364248 | 0.65 | XDH (0.54) | XDHSMN1; SMN2 | |
| SCHEMBL24222220 | 0.63 | XDH (0.45) | XDH | |
| SCHEMBL22381453 | 0.60 | XDH (0.54) | XDHSLC22A12 | |
| SCHEMBL22364231 | 0.58 | XDH (0.54) | XDHSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018005192-A9 | COMPOUNDS AND THEIR USE FOR REDUCING URIC ACID LEVELS | ACQUIST LLC (US) | 2018-05-24 | — | — | WO | disclosed |