Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 4/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 11/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25869080 | 0.81 | MEN1 (0.61) | MEN1KMT2A | |
| SCHEMBL731221 | 0.80 | KDM4E (0.56) | MEN1KMT2A | |
| SCHEMBL16106785 | 0.78 | MCHR1 (0.62) | MCHR1MEN1KMT2A | |
| SCHEMBL5884489 | 0.78 | MCHR1 (0.69) | NCF1MCHR1 | |
| SCHEMBL17430073 | 0.75 | MCHR1 (0.68) | MCHR1 | |
| SCHEMBL15532332 | 0.72 | KMT2A (0.51) | MCHR1MEN1KMT2A | |
| SCHEMBL2089465 | 0.70 | KDM4E (0.44) | NCF1MCHR1MEN1KMT2A | |
| SCHEMBL30082244 | 0.70 | METAP2 (0.63) | NCF1MEN1KMT2A | |
| SCHEMBL672744 | 0.70 | METAP2 (0.63) | NCF1MEN1KMT2A | |
| SCHEMBL17430064 | 0.69 | MCHR1 (0.59) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093695-A1 | FACTOR XIIa INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2018-05-24 | — | — | WO | disclosed |