SCHEMBL672744

SCHEMBL672744

Oc1ccc2cccc(O)c2n1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 2/20 0.63
PLAU P00749 1/20 0.63
NCF1 P14598 1/20 0.63
ALOX12 P18054 3/20 0.61
ALDH1A1 P00352 2/20 0.61
CYP1A2 P05177 1/20 0.61
CYP3A4 P08684 1/20 0.61
CYP2C9 P11712 1/20 0.61
HPGD P15428 1/20 0.61
CYP2C19 P33261 1/20 0.61
HIF1A Q16665 1/20 0.61
HSD17B10 Q99714 1/20 0.61
KMT2A Q03164 7/20 0.57
KDM4E B2RXH2 5/20 0.57
SOS2 Q07890 1/20 0.57
TSHR P16473 2/20 0.56
MMP2 P08253 1/20 0.56
CHRM1 P11229 1/20 0.56
COMT P21964 1/20 0.56
ADRA1A P35348 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30082244 1.00 METAP2 (0.63) METAP2PLAUNCF1ALOX12ALDH1A1
SCHEMBL15442576 0.98 METAP2 (0.61) METAP2PLAUNCF1ALOX12ALDH1A1
SCHEMBL6540982 0.98 METAP2 (0.61) METAP2PLAUNCF1ALOX12ALDH1A1
SCHEMBL1830115 0.98 METAP2 (0.61) METAP2PLAUNCF1ALOX12ALDH1A1
SCHEMBL1496246 0.98 METAP2 (0.61) METAP2PLAUNCF1ALOX12ALDH1A1
Ammonia Solution, Strong SCHEMBL3284067 0.98 METAP2 (0.61) METAP2PLAUNCF1ALOX12ALDH1A1
SCHEMBL413180 0.98 METAP2 (0.61) METAP2PLAUNCF1ALOX12ALDH1A1
SCHEMBL16444064 0.98 METAP2 (0.61) METAP2PLAUNCF1ALOX12ALDH1A1
SCHEMBL8467827 0.98 METAP2 (0.61) METAP2PLAUNCF1ALOX12ALDH1A1
SCHEMBL973003 0.98 METAP2 (0.61) METAP2PLAUNCF1ALOX12ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1421 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4719412-A1 2,8-DIHYDROXYQUINOLINE GLUCURONIDE DERIVATIVES WITH ENHANCED PROPERTIES FOR USE AS ANTICANCER, ANTIVIRAL, ANTIMICROBIAL, AND OTHER THERAPEUTIC APPLICATIONS Westol, LLC (US) 2026-04-08 EP claimed
CN-120081824-A Betti alkali derivative and synthesis method and application thereof 南方医科大学 2025-06-03 CN claimed
CN-119242867-A Antibacterial mildew-proof leather material and preparation method thereof 厦门稀土材料研究所 2025-01-03 CN claimed
WO-2024249983-A1 2,8-DIHYDROXYQUINOLINE GLUCURONIDE DERIVATIVES WITH ENHANCED PROPERTIES FOR USE AS ANTICANCER, ANTIVIRAL, ANTIMICROBIAL, AND OTHER THERAPEUTIC APPLICATIONS WESTOL, LLC (US) 2024-12-05 WO claimed
CN-118883783-A Kit for detecting cold resistance of bees 吉林农业科技学院 2024-11-01 CN claimed
US-20240334723-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2024-10-03 US claimed
US-20240298524-A1 N-Doped Semiconducting Material Comprising Phosphine Oxide Matrix and Metal Dopant NOVALED GMBH (DE) 2024-09-05 US claimed
US-12048175-B2 Organic electroluminescent device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2024-07-23 US claimed
CN-118173765-A Composite lithium iron manganese phosphate positive electrode material, and preparation method and application thereof 曲靖市德方纳米科技有限公司 2024-06-11 CN claimed
US-11993520-B2 Method for preparing a high-purity hydrated nickel sulphate IGO LIMITED (AU) 2024-05-28 US claimed
EP-0046974-A2 Process for the production of high-purity metallic iron Solex Research Corporation of Japan (JP) 1982-03-10 EP claimed
US-4314976-A Purification of nickel sulfate SOUTHWIRE COMPANY (US) 1982-02-09 US claimed
EP-0043919-A2 Process for winning metals from complex ores or scraps Fried. Krupp Gesellschaft mit beschränkter Haftung (DE) 1982-01-20 EP claimed
US-4292181-A COMPLEXING EXXON RESEARCH & ENGINEERING CO. (US) 1981-09-29 US claimed
US-4196278-A Method for the controlled polymerization of polyphenylene oxide polymers GENERAL ELECTRIC COMPANY (US) 1980-04-01 US claimed
US-4173616-A COMPLEXING WITH HYDROXY-OXIME COMPOUNDS SHELL OIL COMPANY (US) 1979-11-06 US claimed
US-4120817-A CARBOXYLIC ACID AND A HYDROXY-OXIME OUTOKUMPU OY (FI) 1978-10-17 US claimed
US-4053553-A FROM BATTERIES, MULTISTAGE LEACHING AND PRECIPITATION WITH AMMONIACAL CARBONATE NIFE JUNGNER AB (SW) 1977-10-11 US claimed
US-3966462-A Recovery of nitric acid soluble transition metals from sulfur and iron containing ores of the same INTERNATIONAL ORE TECHNOLOGY, INC. (US) 1976-06-29 US claimed
US-3956420-A CPOLYOLEFIN COMPOSITION FOR ELECTRICAL INSULATIONFERROCENE, 8-SUBSTITUTED QUINOLINE DAINICHI-NIPPON CABLES, LTD. (JA) 1976-05-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240298524-A1 N-Doped Semiconducting Material Comprising Phosphine Oxide Matrix and Metal Dopant NNMT, PNN, PNMT METAP2 1428/4885PLAU 1706/4885NCF1 870/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.