SCHEMBL20179608

SCHEMBL20179608

CNc1c(OC)cc(CCc2ccc(O)c(SC)c2)cc1OC

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.51
AKR1B1 P15121 2/20 0.51
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 1/20 0.48
POLB P06746 1/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
KMT2A Q03164 1/20 0.48
HSD17B10 Q99714 1/20 0.48
NOS2 P35228 1/20 0.47
TUBB4A P04350 2/20 0.47
TUBB P07437 2/20 0.47
TUBA3C P0DPH7 2/20 0.47
TUBA1B P68363 2/20 0.47
TUBA4A P68366 2/20 0.47
TUBB4B P68371 2/20 0.47
TUBB3 Q13509 2/20 0.47
TUBB2A Q13885 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20179621 0.79 AKR1B1 (0.69) PTPN1AKR1B1KDM4EALDH1A1HPGD
SCHEMBL20179614 0.75 PTPN1 (0.56) PTPN1AKR1B1ALOX15NOS2CALM1
SCHEMBL20179761 0.72 CALM1 (0.57) PTPN1AKR1B1POLBNOS2TUBB4A
SCHEMBL29604390 0.72 PTPN1 (0.82) PTPN1AKR1B1ALDH1A1GAANOS2
SCHEMBL17780116 0.72 PTPN1 (0.82) PTPN1AKR1B1ALDH1A1GAANOS2
SCHEMBL29740697 0.70 PTPN1 (0.79) PTPN1AKR1B1ALDH1A1GAANOS2
Moscatilin SCHEMBL18563068 0.70 AKR1B1 (0.83) PTPN1AKR1B1ALDH1A1GAANOS2
Moscatilin SCHEMBL29449676 0.70 AKR1B1 (0.83) PTPN1AKR1B1ALDH1A1GAANOS2
SCHEMBL29286368 0.68 AKR1B1 (0.81) PTPN1AKR1B1ALDH1A1GAAALOX15
Tristin SCHEMBL29418215 0.68 PTPN1 (1.00) PTPN1AKR1B1ALDH1A1GAANOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018090805-A1 SKIN-PROTECTION COMPOSITION CONTAINING DENDROBIUM-BASED INGREDIENTS HONG KONG BAPTIST UNIVERSITY (CN) 2018-05-24 WO disclosed