Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20179621 | 0.80 | AKR1B1 (0.69) | PTPN1NOS2CALM1AKR1B1GABRA1 | |
| SCHEMBL4459302 | 0.77 | ALOX15 (0.42) | PTGS2CYP3A4CNR1CNR2IGF1R | |
| SCHEMBL4542482 | 0.77 | ALOX15 (0.64) | PTPN1LTA4HTYRAKR1B1IGF1R | |
| SCHEMBL24038795 | 0.76 | ALOX15 (0.41) | PTGS2CYP3A4CNR1CNR2IGF1R | |
| SCHEMBL27666565 | 0.75 | ESR1 (0.46) | CYP3A4ALOX15 | |
| SCHEMBL20179608 | 0.75 | PTPN1 (0.51) | PTPN1NOS2CALM1AKR1B1ALOX15 | |
| SCHEMBL8787271 | 0.73 | XDH (0.40) | AKR1B1CYP3A4GABRA1GABRB2CNR1 | |
| SCHEMBL13899857 | 0.72 | IGF1R (0.41) | CYP3A4CNR1CNR2IGF1RALOX15 | |
| SCHEMBL13899841 | 0.72 | ALOX15 (0.41) | CYP3A4CNR1CNR2IGF1RALOX15 | |
| SCHEMBL24652113 | 0.72 | APP (0.48) | TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018090805-A1 | SKIN-PROTECTION COMPOSITION CONTAINING DENDROBIUM-BASED INGREDIENTS | HONG KONG BAPTIST UNIVERSITY (CN) | 2018-05-24 | — | — | WO | disclosed |