Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 12/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24380625 | 0.94 | ELANE (0.38) | ELANEMEN1KMT2ACA2MAPT | |
| SCHEMBL23336111 | 0.85 | ELANE (0.38) | ELANEMEN1KMT2ACA2KDM4E | |
| SCHEMBL20179806 | 0.82 | ELANE (0.38) | ELANEMEN1KMT2ACA2MAPT | |
| SCHEMBL29756881 | 0.81 | ELANE (0.40) | ELANEMPOMEN1KMT2ACA2 | |
| SCHEMBL20165338 | 0.81 | ELANE (0.40) | ELANEMPOMEN1KMT2ACA2 | |
| SCHEMBL20179641 | 0.79 | ELANE (0.39) | ELANEMEN1KMT2ACA2MAPT | |
| SCHEMBL19132407 | 0.75 | ELANE (0.39) | ELANEMEN1KMT2ACA2MAPT | |
| SCHEMBL29756763 | 0.75 | ELANE (0.39) | ELANEMEN1KMT2ACA2MAPT | |
| SCHEMBL23335926 | 0.73 | ELANE (0.32) | ELANE | |
| SCHEMBL24357428 | 0.72 | PTGS2 (0.36) | ELANEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091153-A1 | NOVEL SUBSTITUTED N-(3-FLUOROPROPYL)-PYRROLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2018-05-24 | — | — | WO | disclosed |