Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859069 | 0.85 | ALDH1A1 (0.50) | HIF1AALDH1A1TSHRTDP1 | |
| SCHEMBL19455882 | 0.85 | ALDH1A1 (0.50) | HIF1AALDH1A1TSHRTDP1 | |
| SCHEMBL6544195 | 0.83 | HIF1A (0.37) | HIF1AALDH1A1TSHR | |
| SCHEMBL10897741 | 0.83 | ALDH1A1 (0.48) | HIF1AALDH1A1TSHRTDP1 | |
| SCHEMBL2452696 | 0.81 | — | — | |
| SCHEMBL229943 | 0.81 | — | — | |
| SCHEMBL9770261 | 0.81 | TSHR (0.55) | HIF1AALDH1A1TSHRTDP1 | |
| SCHEMBL28511546 | 0.79 | TSHR (0.52) | HIF1AALDH1A1TSHRTDP1 | |
| SCHEMBL1682010 | 0.78 | ALDH1A1 (0.43) | HIF1AALDH1A1TSHRTDP1 | |
| SCHEMBL8352114 | 0.77 | TSHR (0.50) | HIF1AALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11254786-B2 | Multifunctional degradable nanoparticles with control over size and functionalities | VANDERBILT UNIVERSITY (US) | 2022-02-22 | — | — | US | disclosed |
| US-10442890-B2 | Multifunctional degradable nanoparticles with control over size and functionalities | VANDERBILT UNIVERSITY (US) | 2019-10-15 | — | — | US | disclosed |
| US-20180142061-A1 | Multifunctional Degradable Nanoparticles with Control over Size and Functionalities | UNIV VANDERBILT (US) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11254786-B2 | Multifunctional degradable nanoparticles with control over size and functionalities | DSTN, PARN, CTSA | HIF1A 491/4885ALDH1A1 1776/4885TSHR 2807/4885 |
| US-10442890-B2 | Multifunctional degradable nanoparticles with control over size and functionalities | DSTN, PARN, CTSA | HIF1A 491/4885ALDH1A1 1776/4885TSHR 2807/4885 |
| US-20180142061-A1 | Multifunctional Degradable Nanoparticles with Control over Size and Functionalities | DSTN, PARN, CTSA | HIF1A 491/4885ALDH1A1 1776/4885TSHR 2807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.