⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19004140 | 0.87 | AKR1B1 (0.31) | — | |
| SCHEMBL2669555 | 0.85 | — | — | |
| SCHEMBL18998304 | 0.81 | — | — | |
| SCHEMBL20179681 | 0.81 | HIF1A (0.44) | — | |
| SCHEMBL21842 | 0.74 | — | — | |
| SCHEMBL1134016 | 0.74 | — | — | |
| SCHEMBL8652672 | 0.74 | — | — | |
| SCHEMBL9407140 | 0.74 | ALDH1A1 (0.38) | — | |
| SCHEMBL6544195 | 0.73 | HIF1A (0.37) | — | |
| SCHEMBL423446 | 0.72 | AKR1B1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3757087-B1 | METHOD FOR MANUFACTURING DIMETHYLOLBUTANAL AND METHOD FOR MANUFACTURING TRIMETHYLOLPROPANE USING SAME | LG CHEMICAL LTD (KR) | 2023-11-15 | — | — | EP | claimed |
| CN-111465590-B | Production method and distillation device of dimethylolbutyraldehyde | LG化学株式会社 | 2023-04-11 | — | — | CN | claimed |
| CN-115677466-A | Preparation method of dimethylolbutyraldehyde | 宁夏百川科技有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-112004791-B | Method for preparing dimethylolbutanal and method for preparing trimethylolpropane using the same | LG化学株式会社 | 2023-01-31 | — | — | CN | claimed |
| CN-110121486-B | Preparation method of trimethylolpropane | LG化学株式会社 | 2022-07-12 | — | — | CN | claimed |
| EP-3539941-B1 | METHOD FOR PREPARING TRIMETHYLOLPROPANE | LG CHEMICAL LTD (KR) | 2021-06-23 | — | — | EP | claimed |
| US-11008274-B2 | Method for manufacturing dimethylolbutanal and method for manufacturing trimethylolpropane using same | LG CHEM, LTD. (KR) | 2021-05-18 | — | — | US | claimed |
| US-10947174-B2 | Method for preparing trimethylolpropane | LG CHEM, LTD. (KR) | 2021-03-16 | — | — | US | claimed |
| US-10913700-B2 | Method for producing dimethylolbutanal and distillation apparatus for producing same | LG CHEM, LTD. (KR) | 2021-02-09 | — | — | US | claimed |
| US-20210009493-A1 | METHOD FOR MANUFACTURING DIMETHYLOLBUTANAL AND METHOD FOR MANUFACTURING TRIMETHYLOLPROPANE USING SAME | LG CHEM, LTD. (KR) | 2021-01-14 | — | — | US | claimed |
| US-6692616-B2 | Method for purifying trimethylolpropane, which is produced by hydrogenation, by means of continuous distillation | BASF AKTIENGESELLSCHAFT (DE) | 2004-02-17 | — | — | US | claimed |
| WO-2004013074-A1 | METHOD FOR INCREASING YIELD IN THE PRODUCTION OF POLYVALENT ALCOHOLS BY SPLITTING BY-PRODUCTS CONTAINING ACETAL | BASF AKTIENGESELLSCHAFT (DE) | 2004-02-12 | — | — | WO | claimed |
| EP-0996605-B1 | Method for the hydrogenation of carbonyl compounds | BASF AG (DE) | 2003-01-29 | — | — | EP | claimed |
| US-20020189926-A1 | Method for purifying trimethylolpropane, which is produced by hydrogenation, by means of continuous distillation | BASF AKTIENGESELLSCHAFT (DE) | 2002-12-19 | — | — | US | claimed |
| EP-1242346-A1 | METHOD FOR PURIFYING TRIMETHYLOLPROPANE, WHICH IS PRODUCED BY HYDROGENATION, BY MEANS OF CONTINUOUS DISTILLATION | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-25 | — | — | EP | claimed |
| JP-2001510172-A | — | — | 2001-07-31 | — | — | JP | claimed |
| WO-2001047847-A1 | METHOD FOR PURIFYING TRIMETHYLOLPROPANE, WHICH IS PRODUCED BY HYDROGENATION, BY MEANS OF CONTINUOUS DISTILLATION | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-05 | — | — | WO | claimed |
| US-6207865-B1 | HYDROGENATION OF ALDEHYDES OBTAINED BY THE OXO SYNTHESIS OR THE ALDOL REACTION, RANEY COPPER CATALYST IS EMPLOYED IN THE FORM OF NUGGETS. | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-27 | — | — | US | claimed |
| EP-0996605-A1 | METHOD FOR THE HYDROGENATION OF CARBONYL COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-03 | — | — | EP | claimed |
| WO-1999003801-A1 | METHOD FOR THE HYDROGENATION OF CARBONYL COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-28 | — | — | WO | claimed |