Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 11/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 11/20 | 0.47 |
| ▸ | GNAO1 | P09471 | 10/20 | 0.47 |
| ▸ | NAAA | Q02083 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850134 | 0.89 | GNAI3 (0.47) | GNAI3GNAI1GNAO1NAAAFAAH | |
| SCHEMBL23658148 | 0.88 | CHRNB2 (0.37) | GNAI3GNAI1GNAO1NAAAFAAH | |
| SCHEMBL6285457 | 0.87 | GNAI3 (0.45) | GNAI3GNAI1GNAO1NAAAFAAH | |
| SCHEMBL25021919 | 0.83 | GNAI3 (0.48) | GNAI3GNAI1GNAO1NAAAFAAH | |
| SCHEMBL25022737 | 0.83 | GNAI3 (0.48) | GNAI3GNAI1GNAO1NAAAFAAH | |
| SCHEMBL25022773 | 0.83 | GNAI3 (0.48) | GNAI3GNAI1GNAO1NAAAFAAH | |
| SCHEMBL8118934 | 0.82 | GNAI3 (0.40) | GNAI3GNAI1GNAO1NAAAFAAH | |
| SCHEMBL30641647 | 0.81 | GNAI3 (0.49) | GNAI3GNAI1GNAO1NAAAFAAH | |
| SCHEMBL27862405 | 0.79 | GNAI3 (0.47) | GNAI3GNAI1GNAO1NAAAFAAH | |
| SCHEMBL25022230 | 0.76 | GNAI3 (0.46) | GNAI3GNAI1GNAO1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093695-A1 | FACTOR XIIa INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2018-05-24 | — | — | WO | disclosed |