Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 6/20 | 0.33 |
| ▸ | SSTR1 | P30872 | 3/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22954521 | 0.87 | SSTR4 (0.33) | SSTR4SSTR1SMN1; SMN2MAPT | |
| SCHEMBL22166895 | 0.85 | — | — | |
| SCHEMBL22329079 | 0.80 | HRH3 (0.31) | ALDH1A1 | |
| SCHEMBL15888621 | 0.78 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL13162618 | 0.78 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL13162638 | 0.78 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL20179859 | 0.76 | — | — | |
| SCHEMBL12108445 | 0.76 | CHRM4 (0.45) | CHRM4CHRM5CHRM1CHRM3SMN1; SMN2 | |
| SCHEMBL21367217 | 0.73 | NCF1 (0.35) | — | |
| SCHEMBL18391577 | 0.73 | NCF1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018090862-A1 | DIHYDROPYRIMIDINE COMPOUND AND PREPARATION METHOD AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2018-05-24 | — | — | WO | disclosed |