Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.58 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.51 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2735422 | 0.92 | GPR119 (0.67) | GPR119USP30KMT2ANPBWR1MCHR1 | |
| SCHEMBL699608 | 0.90 | GPR119 (0.58) | GPR119USP30PIK3CDCHEK2ALDH1A1 | |
| SCHEMBL31142651 | 0.90 | ALDH1A1 (0.60) | GPR119USP30PIK3CDALDH1A1 | |
| SCHEMBL15376614 | 0.90 | GPR119 (0.58) | GPR119USP30PIK3CDCHEK2ALDH1A1 | |
| SCHEMBL699609 | 0.90 | GPR119 (0.58) | GPR119USP30PIK3CDCHEK2ALDH1A1 | |
| SCHEMBL6189661 | 0.90 | GPR119 (0.58) | GPR119USP30PIK3CDCHEK2ALDH1A1 | |
| SCHEMBL12788093 | 0.89 | USP30 (0.53) | GPR119USP30KMT2ANPBWR1MCHR1 | |
| SCHEMBL24467408 | 0.88 | GPR119 (0.57) | GPR119USP30PIK3CDCHEK2ALDH1A1 | |
| SCHEMBL20168872 | 0.88 | GPR119 (0.57) | GPR119USP30PIK3CDCHEK2ALDH1A1 | |
| SCHEMBL3377761 | 0.88 | GPR119 (0.57) | GPR119USP30KMT2APIK3CDCHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091153-A1 | NOVEL SUBSTITUTED N-(3-FLUOROPROPYL)-PYRROLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2018-05-24 | — | — | WO | disclosed |