Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.52 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.44 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.44 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.44 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26240668 | 0.91 | LTA4H (0.49) | LTA4HSCN8AALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL11953341 | 0.87 | KDM4E (0.58) | LTA4HS1PR1S1PR3S1PR2ALDH1A1 | |
| SCHEMBL8851568 | 0.87 | LTA4H (0.63) | LTA4HALDH1A1SMN1; SMN2TOP2A | |
| SCHEMBL537492 | 0.86 | KDM4E (0.62) | LTA4HSCN8AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL27573257 | 0.85 | L3MBTL1 (0.50) | LTA4HS1PR1S1PR3S1PR2ALDH1A1 | |
| SCHEMBL20493693 | 0.83 | LTA4H (0.51) | LTA4HS1PR1S1PR3S1PR2ALDH1A1 | |
| SCHEMBL11954288 | 0.83 | SCN8A (0.53) | LTA4HSCN8AS1PR1S1PR3S1PR2 | |
| SCHEMBL20197071 | 0.82 | HDAC3 (0.63) | LTA4HSCN8AALDH1A1HPGD | |
| SCHEMBL3057335 | 0.81 | LTA4H (0.62) | LTA4HALDH1A1SMN1; SMN2 | |
| SCHEMBL5940295 | 0.80 | LTA4H (0.50) | LTA4HS1PR1ALDH1A1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093947-A1 | MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-05-24 | — | — | WO | disclosed |