Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.49 |
| ▸ | NT5E | P21589 | 5/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20180089 | 0.89 | NT5E (0.53) | ADORA3NT5EADORA2AADORA1ADORA2B | |
| SCHEMBL20168089 | 0.80 | NT5E (0.66) | ADORA3NT5EADORA2AADORA1ADORA2B | |
| SCHEMBL21766000 | 0.79 | ADORA3 (0.49) | ADORA3NT5EADORA2AADORA1ADORA2B | |
| SCHEMBL23633915 | 0.79 | NT5E (0.71) | ADORA3NT5EADORA2AADORA1 | |
| SCHEMBL20180092 | 0.79 | ADORA1 (0.46) | ADORA3NT5EADORA2AADORA1ADORA2B | |
| SCHEMBL21766013 | 0.77 | NT5E (0.47) | ADORA3NT5EADORA2AADORA1ADORA2B | |
| SCHEMBL22215061 | 0.77 | NT5E (0.71) | ADORA3NT5EADORA2AADORA1 | |
| SCHEMBL21766031 | 0.76 | NT5E (0.46) | ADORA3NT5EADORA2AADORA1ADORA2B | |
| SCHEMBL20168148 | 0.76 | NT5E (0.74) | ADORA3NT5EADORA2AADORA1ADORA2B | |
| SCHEMBL20168732 | 0.76 | NT5E (0.69) | ADORA3NT5EADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018094148-A1 | INHIBITORS OF CD73-MEDIATED IMMUNOSUPPRESSION | ARCUS BIOSCIENCES, INC. (US) | 2018-05-24 | — | — | WO | disclosed |