Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 10/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14091149 | 0.86 | SLC6A2 (0.50) | ADRB3ADRB2ADRB1SLC6A2SLC6A4 | |
| SCHEMBL24615892 | 0.86 | SLC6A2 (0.50) | ADRB3ADRB2ADRB1SLC6A2SLC6A4 | |
| SCHEMBL16959061 | 0.83 | SLC6A4 (0.47) | SLC6A2SLC6A4SLC6A3HPGDAOC3 | |
| SCHEMBL13849942 | 0.81 | ADRB1 (0.48) | ADRB3ADRB2ADRB1SLC2A1ACP3 | |
| SCHEMBL14402491 | 0.81 | ADRB1 (0.48) | ADRB3ADRB2ADRB1SLC2A1ACP3 | |
| SCHEMBL13849930 | 0.81 | ADRB1 (0.48) | ADRB3ADRB2ADRB1SLC2A1ACP3 | |
| SCHEMBL6690481 | 0.81 | ADRB1 (0.48) | ADRB3ADRB2ADRB1SLC2A1ACP3 | |
| SCHEMBL281883 | 0.80 | IDO1 (0.48) | ADRB3ADRB2ADRB1SLC2A1ACP3 | |
| SCHEMBL3156406 | 0.80 | IDO1 (0.48) | ADRB3ADRB2ADRB1SLC2A1ACP3 | |
| SCHEMBL282798 | 0.80 | IDO1 (0.48) | ADRB3ADRB2ADRB1SLC2A1ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018094148-A1 | INHIBITORS OF CD73-MEDIATED IMMUNOSUPPRESSION | ARCUS BIOSCIENCES, INC. (US) | 2018-05-24 | — | — | WO | disclosed |