Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14091149 | 1.00 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3ADRB3ADRB1 | |
| SCHEMBL20180124 | 0.86 | ADRB3 (0.45) | SLC6A2SLC6A4SLC6A3ADRB3ADRB1 | |
| SCHEMBL9195198 | 0.81 | SLC6A4 (0.52) | SLC6A2SLC6A4SLC6A3HPGDAOC3 | |
| SCHEMBL16759671 | 0.81 | PYGL (0.39) | SLC6A2SLC6A4SLC6A3ADRB1ADRB2 | |
| SCHEMBL1935468 | 0.80 | AOC3 (0.45) | SLC6A2SLC6A4SLC6A3ADRB3ADRB1 | |
| SCHEMBL17071836 | 0.80 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3ADRB3ADRB1 | |
| SCHEMBL16771184 | 0.80 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3ADRB3ADRB1 | |
| SCHEMBL16952699 | 0.80 | SLC6A4 (0.51) | SLC6A2SLC6A4SLC6A3HPGDAOC3 | |
| SCHEMBL25832940 | 0.80 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3ADRB3ADRB1 | |
| SCHEMBL3482675 | 0.79 | LMNA (0.57) | SLC6A2SLC6A4ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022148422-A1 | BRIDGED COMPOUNDS AS KRAS G12D INHIBITOR AND DEGRADER AND THE USE THEREOF | BEIGENE, LTD. (KY) | 2022-07-14 | — | — | WO | disclosed |