SCHEMBL20180139

SCHEMBL20180139

CC1(C)OB(c2cccc(-n3ccc4cc(-c5ccccc5)ccc43)c2)OC1(C)C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 9/20 0.49
LPL P06858 8/20 0.49
HTR6 P50406 1/20 0.36
HSD11B1 P28845 1/20 0.36
IRAK4 Q9NWZ3 1/20 0.35
PLA2G4A P47712 1/20 0.34
ROCK2 O75116 1/20 0.34
PIM1 P11309 1/20 0.34
PIM3 Q86V86 1/20 0.34
NTSR1 P30989 1/20 0.34
FAAH O00519 1/20 0.33
COMT P21964 1/20 0.33
LDHA P00338 1/20 0.33
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC2 Q92769 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20180344 0.88 LIPG (0.40) LIPGLPLHTR6HSD11B1IRAK4
SCHEMBL20180237 0.86 LIPG (0.37) LIPGLPLPLA2G4ANTSR1
SCHEMBL17177971 0.86 LIPG (0.48) LIPGLPLHTR6HSD11B1IRAK4
SCHEMBL19119810 0.85 LPL (0.43) LIPGLPLIRAK4ROCK2PIM1
SCHEMBL15533400 0.84 LPL (0.46) LIPGLPLIRAK4PLA2G4AHDAC3
SCHEMBL20180416 0.83 LPL (0.44) LIPGLPLIRAK4ROCK2PIM1
SCHEMBL441742 0.80 LIPG (0.52) LIPGLPLHSD11B1IRAK4FAAH
SCHEMBL24770337 0.78 LIPG (0.72) LIPGLPLIRAK4
SCHEMBL13700830 0.78 LIPG (0.73) LIPGLPLIRAK4KEAP1NFE2L2
SCHEMBL15197437 0.78 LIPG (0.73) LIPGLPLIRAK4KEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018093107-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 2018-05-24 WO disclosed