Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 4/20 | 0.47 |
| ▸ | KHK | P50053 | 2/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20180230 | 0.90 | NR3C1 (0.59) | NR3C1KHKIRAK4CYP11B2PGR | |
| SCHEMBL20180412 | 0.89 | NR3C1 (0.61) | NR3C1KHKIRAK4CYP11B2PGR | |
| SCHEMBL20180350 | 0.89 | NR3C1 (0.45) | NR3C1KHKIRAK4PGRNPC1 | |
| SCHEMBL20180178 | 0.83 | NR3C1 (0.55) | NR3C1KHKIRAK4CYP11B2PGR | |
| SCHEMBL20180183 | 0.83 | NPC1 (0.40) | NR3C1KHKIRAK4NPC1RAB9A | |
| SCHEMBL20180188 | 0.83 | NR3C1 (0.48) | NR3C1KHKIRAK4PGR | |
| SCHEMBL20180181 | 0.79 | NR3C1 (0.44) | NR3C1KHKIRAK4PGR | |
| SCHEMBL26011218 | 0.79 | NR3C1 (0.40) | NR3C1KHKCYP11B1CYP11B2LRRK2 | |
| SCHEMBL20180414 | 0.79 | NR3C1 (0.52) | NR3C1KHKIRAK4PGR | |
| SCHEMBL729956 | 0.78 | KDM4E (0.56) | NR3C1KHKCYP11B1CYP11B2LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093107-A1 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | 주식회사 두산 | 2018-05-24 | — | — | WO | disclosed |