Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20180533 | 0.87 | ALDH1A1 (0.39) | SIRT2SIRT1ALDH1A1HTTMPO | |
| SCHEMBL20180548 | 0.76 | MEN1 (0.43) | SIRT2SIRT1ALDH1A1HTTMPO | |
| SCHEMBL26858235 | 0.70 | ALDH1A1 (0.47) | SIRT2SIRT1ALDH1A1HTTABCB1 | |
| SCHEMBL30675132 | 0.70 | ALDH1A1 (0.47) | SIRT2SIRT1ALDH1A1HTTABCB1 | |
| SCHEMBL20180309 | 0.68 | ABCG2 (0.41) | SIRT2SIRT1ALDH1A1HTTABCB1 | |
| SCHEMBL17454730 | 0.66 | MAPT (0.43) | SIRT2ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL20918447 | 0.66 | ALDH1A1 (0.56) | ALDH1A1HTTABCB1ABCG2ABCC1 | |
| SCHEMBL23447540 | 0.66 | EPHX2 (0.42) | SIRT2SIRT1ALDH1A1EGFRMEN1 | |
| SCHEMBL20615351 | 0.65 | SIRT2 (0.42) | SIRT2SIRT1ALDH1A1KDM4EHDAC3 | |
| SCHEMBL24672219 | 0.64 | ALDH1A1 (0.42) | SIRT2SIRT1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093107-A1 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | 주식회사 두산 | 2018-05-24 | — | — | WO | disclosed |