Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ACACB | O00763 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 2/20 | 0.46 |
| ▸ | ESRRB | O95718 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4475119 | 0.87 | LMNA (0.64) | PLK1POLBGAAALDH1A1LMNA | |
| SCHEMBL1405105 | 0.84 | ACACB (0.52) | PLK1POLBALDH1A1LMNAACACB | |
| SCHEMBL10951282 | 0.83 | PLK1 (0.72) | PLK1POLBCTDSP1GAAALDH1A1 | |
| SCHEMBL27947108 | 0.81 | EPHX2 (0.55) | POLBALDH1A1LMNAACACBMLYCD | |
| SCHEMBL506515 | 0.80 | HDAC3 (0.58) | POLBALDH1A1LMNAACACB | |
| SCHEMBL10950404 | 0.80 | PLK1 (0.68) | PLK1POLBCTDSP1GAAALDH1A1 | |
| SCHEMBL397853 | 0.80 | LMNA (0.56) | POLBGAAALDH1A1LMNATDP1 | |
| SCHEMBL13483863 | 0.78 | RAB9A (0.57) | LMNANPC1RAB9AKMT2ATRPV1 | |
| SCHEMBL23116863 | 0.78 | GFER (0.53) | GAAALDH1A1LMNAACACBNPC1 | |
| SCHEMBL12188582 | 0.78 | EPHX2 (0.50) | GAAALDH1A1ACACBMLYCDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3922639-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2021-12-15 | — | — | EP | disclosed |
| EP-3298027-B1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-04-28 | — | — | EP | disclosed |
| WO-2018093920-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | MERIAL, INC. (US) | 2018-05-24 | — | — | WO | disclosed |