SCHEMBL2018047

SCHEMBL2018047

CO[Si](CCCOCC1CO1)(OC)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
ALDH1A1 P00352 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
GLA P06280 1/20 0.38
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
HIF1A Q16665 1/20 0.33
MAPK1 P28482 1/20 0.33
MGLL Q99685 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11290142 1.00 TSHR (0.46) TSHRSMN1; SMN2ALDH1A1TDP1MEN1
SCHEMBL9560206 0.96 TSHR (0.49) TSHRSMN1; SMN2ALDH1A1TDP1MEN1
SCHEMBL17373031 0.93 TSHR (0.50) TSHRSMN1; SMN2ALDH1A1TDP1MEN1
SCHEMBL9721065 0.92 TDP1 (0.42) TSHRSMN1; SMN2ALDH1A1TDP1MEN1
SCHEMBL14839836 0.88 TSHR (0.45) TSHRSMN1; SMN2ALDH1A1TDP1MEN1
SCHEMBL17236330 0.86 TSHR (0.44) TSHRSMN1; SMN2ALDH1A1TDP1MEN1
SCHEMBL1713138 0.86 SMN1; SMN2 (0.46) TSHRSMN1; SMN2ALDH1A1TDP1MEN1
SCHEMBL23701339 0.86 TSHR (0.46) TSHRSMN1; SMN2ALDH1A1TDP1MEN1
SCHEMBL28554486 0.84 TSHR (0.50) TSHRSMN1; SMN2ALDH1A1TDP1MEN1
SCHEMBL6656047 0.84 TSHR (0.50) TSHRSMN1; SMN2ALDH1A1TDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116075559-B Optical article with low interference fringe and coating agent composition thereof 日本精化株式会社 2023-12-05 CN claimed
US-20230348750-A1 LOW INTERFERENCE FRINGE OPTICAL ARTICLE AND COATING AGENT COMPOSITION THEREOF NIPPON FINE CHEMICAL CO., LTD. (JP) 2023-11-02 US claimed
US-6391433-B1 None US disclosed
US-12640467-B2 Decorative radome and method of producing the same Motherson Innovations Company Limited (GB) 2026-05-26 US disclosed
EP-4142048-B1 DECORATIVE PVD COATED ITEMS AND RADOMES AND METHODS OF MAKING SAME MOTHERSON INNOVATIONS CO LTD (GB) 2026-05-06 EP disclosed
EP-4730561-A2 FIRST SURFACE DECORATIVEELEMENT Motherson Innovations Company Limited (GB) 2026-04-22 EP disclosed
US-12577652-B2 Decorative coating excluding a base hard-coat Motherson Innovations Company Limited (GB) 2026-03-17 US disclosed
EP-4046239-B1 FIRST SURFACE DECORATIVE ELEMENT MOTHERSON INNOVATIONS CO LTD (GB) 2026-01-28 EP disclosed
EP-4664680-A2 DECORATIVE RADOME AND METHOD OF PRODUCING A DECORATIVE RADOME Motherson Innovations Company Limited (GB) 2025-12-17 EP disclosed
EP-4005022-B1 FIRST SURFACE OR SECOND SURFACE DECORATIVE RADOME MOTHERSON INNOVATIONS CO LTD (GB) 2025-09-17 EP disclosed
US-20250282945-A1 CURABLE RESIN COMPOSITION AND ELECTRONIC COMPONENT DEVICE RESONAC CORPORATION (JP) 2025-09-11 US disclosed
US-4835023-A Ornamental articles having coating membrane TORAY INDUSTRIES, INC. (JP) 1989-05-30 US disclosed
US-4786667-A HEAT AND WEATHER RESISTANCE, SEALANT TOSHIBA SILICONE CO., LTD. (JP) 1988-11-22 US disclosed
US-4765729-A POLYSILOXANES AS SURFACE COATINGS; SCRATCH RESISTANCE TORAY INDUSTRIES, INC. (JP) 1988-08-23 US disclosed
EP-0278060-A2 Anti-reflection optical article and process of producing the same TORAY INDUSTRIES, INC. (JP) 1988-08-17 EP disclosed
EP-0207775-A2 Ornamental articles having a coating membrane TORAY INDUSTRIES, INC. (JP) 1987-01-07 EP disclosed
US-4590117-A HARDENED LAYERS OF OXIDES OF ALUMINUM, TITANIUM AND/OR ZIRCONIUM AND A POLYSILOXANE; DYEABILITY; LENS TORAY INDUSTRIES, INC. (JP) 1986-05-20 US disclosed
US-4439557-A SILYL SUBSTITUTED ACRYLATES, CURING CATALYST TORAY INDUSTRIES, INCORPORATED (JP) 1984-03-27 US disclosed
US-4374158-A SURFACE LAYER, CONSISTING OF INORGANIC PARTICLES, TREATED WITH ACTIVATED GASES TORAY INDUSTRIES, INC. (JP) 1983-02-15 US disclosed
EP-0065388-A1 Coating composition TORAY INDUSTRIES, INC. (JP) 1982-11-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12640467-B2 Decorative radome and method of producing the same RAD1, RAD18, RAD54L TSHR 1637/4885SMN1; SMN2 3470/4885ALDH1A1 1084/4885
US-12577652-B2 Decorative coating excluding a base hard-coat PRNP, NCL, ULK2 TSHR 3379/4885SMN1; SMN2 1006/4885ALDH1A1 3628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.