Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11290142 | 0.86 | TSHR (0.46) | TSHRSMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL2018047 | 0.86 | TSHR (0.46) | TSHRSMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL6656047 | 0.84 | TSHR (0.50) | TSHRSMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL28554486 | 0.84 | TSHR (0.50) | TSHRSMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL17373030 | 0.82 | TSHR (0.52) | TSHRSMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL9560206 | 0.82 | TSHR (0.49) | TSHRSMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL18707711 | 0.82 | TSHR (0.47) | TSHRSMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL18094268 | 0.82 | TSHR (0.41) | TSHRSMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL3922211 | 0.81 | TSHR (0.41) | TSHRSMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL9721065 | 0.80 | TDP1 (0.42) | TSHRSMN1; SMN2ALDH1A1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807758-B2 | Siloxane polymer and method of producing siloxane polymer | JNC CORPORATION (JP) | 2023-11-07 | — | — | US | disclosed |
| US-20210238419-A1 | SILOXANE POLYMER AND METHOD OF PRODUCING SILOXANE POLYMER | JNC CORPORATION (JP) | 2021-08-05 | — | — | US | disclosed |