Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11290142 | 0.96 | TSHR (0.46) | TSHRALDH1A1TDP1SMN1; SMN2MEN1 | |
| SCHEMBL2018047 | 0.96 | TSHR (0.46) | TSHRALDH1A1TDP1SMN1; SMN2MEN1 | |
| SCHEMBL9721065 | 0.90 | TDP1 (0.42) | TSHRALDH1A1TDP1SMN1; SMN2MEN1 | |
| SCHEMBL17373031 | 0.89 | TSHR (0.50) | TSHRALDH1A1TDP1SMN1; SMN2MEN1 | |
| SCHEMBL14839836 | 0.84 | TSHR (0.45) | TSHRALDH1A1TDP1SMN1; SMN2MEN1 | |
| SCHEMBL17236330 | 0.83 | TSHR (0.44) | TSHRALDH1A1TDP1SMN1; SMN2MEN1 | |
| SCHEMBL1713138 | 0.83 | SMN1; SMN2 (0.46) | TSHRALDH1A1TDP1SMN1; SMN2MEN1 | |
| SCHEMBL23701339 | 0.82 | TSHR (0.46) | TSHRALDH1A1TDP1SMN1; SMN2MEN1 | |
| SCHEMBL5265710 | 0.81 | TDP1 (0.45) | TSHRALDH1A1TDP1SMN1; SMN2MEN1 | |
| SCHEMBL4364354 | 0.81 | SMN1; SMN2 (0.38) | TSHRALDH1A1TDP1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5209871-A | Reacting a polyether diamine and a epoxysilane, alkali metal salt | FORD MOTOR COMPANY (US) | 1993-05-11 | — | — | US | disclosed |
| US-5093389-A | Epoxy-Terminated Polysiloxane, Silanol-Terminated Polysiloxane Aminoxysilicon Compound | TOSHIBA SILICONE CO., LTD. (JP) | 1992-03-03 | — | — | US | disclosed |