Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CCR4 | P51679 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13757013 | 0.87 | MAPT (0.45) | MAPTCCR4ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL20180480 | 0.82 | ALDH1A1 (0.42) | MAPTCCR4ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL25718308 | 0.79 | MAPT (0.40) | MAPTCCR4ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL21388465 | 0.79 | MAPT (0.47) | MAPTCCR4ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL24123758 | 0.79 | HRH4 (0.41) | MAPTCCR4KDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL20180619 | 0.77 | DRD2 (0.42) | MAPTCCR4ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL21388477 | 0.74 | KDM4E (0.39) | MAPTALDH1A1KDM4ESMN1; SMN2POLB | |
| SCHEMBL8275459 | 0.74 | MAPT (0.46) | MAPTALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL20180504 | 0.71 | NPSR1 (0.53) | MAPTCCR4ALDH1A1KDM4EKMT2A | |
| SCHEMBL14137696 | 0.71 | ALDH1A1 (0.41) | MAPTALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018090939-A1 | 8,9-DIHYDROIMIDAZOLE[1,2-A]PYRIMIDO[5,4-E]PYRIMIDINE-5(6H)-KETONE COMPOUND | 上海瑛派药业有限公司 | 2018-05-24 | — | — | WO | disclosed |