Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 4/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | P4HB | P07237 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MLNR | O43193 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8181399 | 0.88 | CACNA1G (0.44) | CACNA1GCAPN1KDM1ADRD2DRD4 | |
| SCHEMBL20977566 | 0.80 | CACNA1G (0.39) | CACNA1GCAPN1KDM1ADRD2DRD4 | |
| SCHEMBL20977455 | 0.79 | CACNA1G (0.43) | CACNA1GCAPN1KDM1ADRD2DRD4 | |
| SCHEMBL8664410 | 0.73 | HDAC8 (0.54) | CACNA1GHDAC8MAPT | |
| SCHEMBL25455638 | 0.69 | CYP19A1 (0.42) | KDM1ADRD2DRD4GAAKMT2A | |
| SCHEMBL5218486 | 0.68 | CACNA1G (0.41) | CACNA1GKMT2AMAPTPKM | |
| SCHEMBL313093 | 0.68 | CACNA1G (0.42) | CACNA1GCAPN1KDM1ADRD2DRD4 | |
| SCHEMBL22546605 | 0.65 | NPC1 (0.45) | DRD2GAAKDM4E | |
| SCHEMBL13876425 | 0.64 | MLNR (0.53) | KDM1ADRD2DRD4BCHEKDM4E | |
| SCHEMBL13399671 | 0.63 | GAA (0.50) | CAPN1KDM1ADRD2DRD4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10264766-B2 | Antimicrobial compounds and compositions, and uses thereof | Akeso Biomedical, Inc. (US) | 2019-04-23 | — | — | US | disclosed |
| US-20180199550-A1 | ANTIMICROBIAL COMPOUNDS AND COMPOSITIONS, AND USES THEREOF | Akeso Biomedical, Inc. | 2018-07-19 | — | — | US | disclosed |
| US-20180139932-A1 | ANTIMICROBIAL COMPOUNDS AND COMPOSITIONS, AND USES THEREOF | Akeso Biomedical, Inc. | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180139932-A1 | ANTIMICROBIAL COMPOUNDS AND COMPOSITIONS, AND USES THEREOF | TYR, TH, DDC | CACNA1G 2278/4885CAPN1 4778/4885KDM1A 711/4885 |
| US-10264766-B2 | Antimicrobial compounds and compositions, and uses thereof | TYR, TH, DDC | CACNA1G 2309/4885CAPN1 4777/4885KDM1A 715/4885 |
| US-20180199550-A1 | ANTIMICROBIAL COMPOUNDS AND COMPOSITIONS, AND USES THEREOF | TYR, TH, DDC | CACNA1G 2278/4885CAPN1 4778/4885KDM1A 711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.