Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.32 |
| ▸ | ALB | P02768 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22779434 | 0.83 | JAK2 (0.36) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL20156720 | 0.83 | FGFR1 (0.34) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL20978401 | 0.82 | FGFR1 (0.32) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL20404869 | 0.81 | DHFR (0.41) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL20806276 | 0.80 | FGFR1 (0.33) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL24420602 | 0.80 | FGFR1 (0.33) | FGFR1SLC22A6 | |
| SCHEMBL784164 | 0.79 | ADORA2A (0.36) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL8840757 | 0.78 | FGFR1 (0.35) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL23352431 | 0.77 | FGFR1 (0.32) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL19597942 | 0.76 | LMNA (0.35) | FGFR1LMNATHRBMTORMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022099055-A1 | TEMPLATE ASSEMBLY BY PROXIMITY-ENHANCED REACTIVITY VIA METABOLIC LABELING | THE GENERAL HOSPITAL CORPORATION (US) | 2022-05-12 | — | — | WO | disclosed |
| US-20180142107-A1 | SURFACE COATING COMPOSITION | STO SE & CO. KGAA (DE) | 2018-05-24 | — | — | US | disclosed |