SCHEMBL2018066

SCHEMBL2018066

N=C(N)Nc1ncc[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11153812 0.98 KLK1 (0.43)
SCHEMBL241675 0.79
SCHEMBL28057416 0.79
Ammonia Solution, Strong SCHEMBL29001621 0.78 FDPS (0.44)
SCHEMBL7342758 0.74 FDPS (0.48)
SCHEMBL8819697 0.74 FDPS (0.48)
Acetic Acid SCHEMBL29250458 0.73 FFAR2 (0.43)
SCHEMBL5333624 0.73 FDPS (0.41)
SCHEMBL170782 0.72
SCHEMBL3072865 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9272037-B2 Method to treat premature ejaculation in humans TRINITY LABORATORIES, INC. (US) 2016-03-01 US claimed
US-20140296262-A1 Method to Treat Premature Ejaculation in Humans TRINITY LABORATORIES, INC. (US) 2014-10-02 US claimed
US-20090215810-A1 Method to Treat Premature Ejaculation in Humans TRINITY LABORATORIES, INC. (US) 2009-08-27 US claimed
EP-1969117-A4 A METHOD TO TREAT PREMATURE EJACULATION IN HUMANS TRINITY LAB INC (US) 2008-12-17 EP claimed
EP-1969117-A2 A METHOD TO TREAT PREMATURE EJACULATION IN HUMANS Trinity Laboratories, Inc. (US) 2008-09-17 EP claimed
WO-2007070779-A2 A METHOD TO TREAT PREMATURE EJACULATION IN HUMANS TRINITY LABORATORIES, INC. (US) 2007-06-21 WO claimed
US-20040235954-A1 Method for treatment of premature ejaculation in humans JEFFERSON BANK 2004-11-25 US claimed
WO-2004043365-A2 METHOD FOR TREATMENT OF PREMATURE EJACULATION IN HUMANS AZAYA THERAPEUTICS, INC. (US) 2004-05-27 WO claimed
EP-0638671-B1 Compositions for polyolefin fibers having improved flame-resistance and no corrosive properties MONTELL NORTH AMERICA INC (US) 1998-05-20 EP claimed
US-5536572-A CONTAINING AMINE-METAL COMPLEX, POLYDIISOPROPYLBENZENE, ORGANIC EPOXIDE MONTELL NORTH AMERICA INC. (US) 1996-07-16 US claimed
US-5494951-A BISMUTH OR ANTIMONY COMPLEX; POLY-1,4-DIISOPROPYLBENZENE, AND ORGANIC EPOXIDE MONTELL NORTH AMERICA INC. (US) 1996-02-27 US claimed
EP-0638671-A2 Compositions for polyolefin fibers having improved flame-resistance and no corrosive properties MONTELL NORTH AMERICA INC. (US) 1995-02-15 EP claimed
EP-0262448-B1 IMIDAZOLYLGUANIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM HEUMANN PHARMA GMBH &amp; CO (DE) 1991-12-18 EP claimed
US-4912119-A Cardiovascular disorders HEUMANN PHARMA GMBH & CO. (DE) 1990-03-27 US claimed
JP-7179677-A None JP disclosed
CN-119481185-A Composite proton exchange membrane based on guanidine salt/imidazole derivative for high-temperature fuel cell and preparation method thereof 常州大学 2025-02-18 CN disclosed
CN-107428795-B Method for tagging DNA encoding libraries X-化学有限公司 2021-06-18 CN disclosed
US-4234735-A ANTIHISTAMINES, ANTISECRETORY AGENTS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-11-18 US disclosed
EP-0017152-A1 Novel heterocyclic substituted pyrazinoylguanidines, processes for preparing and a pharmaceutical composition containing the same MERCK & CO. INC. (US) 1980-10-15 EP disclosed
US-4165377-A ANTIHISTAMINES, ANTISECRETORY ICI AMERICAS INC. (US) 1979-08-21 US disclosed