Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13702362 | 0.78 | CYP2C9 (0.53) | ALDH1A1CYP2D6KDM4EGAAPOLB | |
| SCHEMBL446124 | 0.78 | CYP3A4 (0.51) | ABL1BCRALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL1654886 | 0.78 | EGLN2 (0.53) | ABL1BCRALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL13701724 | 0.78 | MAPK14 (0.49) | CYP2D6GAAMAPK14MAPT | |
| SCHEMBL427012 | 0.77 | ALDH1A1 (0.58) | ABL1BCRALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL2831921 | 0.77 | ABL1 (0.49) | ABL1BCRALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL12015770 | 0.74 | ABL1 (0.47) | ABL1BCRALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL11988642 | 0.74 | FGFR1 (0.49) | ABL1BCRALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL11988213 | 0.73 | DRD2 (0.57) | ALDH1A1CYP3A4CYP2D6CYP1A2LMNA | |
| SCHEMBL13702377 | 0.71 | POLB (0.54) | ALDH1A1CYP3A4CYP2D6CYP1A2CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093797-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF ABERRANT ANGIOGENESIS | THE SCHEPENS EYE RESEARCH INSTITUTE, INC. (US) | 2018-05-24 | — | — | WO | disclosed |