Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC42 | P60953 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | CASP6 | P55212 | 1/20 | 0.69 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | BRD3 | Q15059 | 7/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | RB1 | P06400 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5454054 | 1.00 | CDC42 (1.00) | CDC42GAACASP6PRMT5CYP2D6 | |
| SCHEMBL12922440 | 0.90 | CDC42 (0.82) | CDC42GAACASP6PRMT5CYP2D6 | |
| SCHEMBL5449921 | 0.89 | CDC42 (0.80) | CDC42GAACASP6PRMT5CYP2D6 | |
| SCHEMBL24863190 | 0.87 | CDC42 (0.77) | CDC42GAACASP6PRMT5CYP2D6 | |
| SCHEMBL15167010 | 0.87 | CDC42 (0.77) | CDC42GAACASP6PRMT5CYP2D6 | |
| SCHEMBL5461141 | 0.87 | CDC42 (0.76) | CDC42GAACASP6PRMT5CYP2D6 | |
| SCHEMBL22135739 | 0.86 | CDC42 (0.76) | CDC42GAACASP6PRMT5CYP2D6 | |
| SCHEMBL5461734 | 0.86 | CDC42 (0.76) | CDC42GAACASP6PRMT5CYP2D6 | |
| SCHEMBL31721161 | 0.85 | CDC42 (0.74) | CDC42GAACASP6PRMT5CYP2D6 | |
| SCHEMBL31721117 | 0.85 | CDC42 (0.74) | CDC42GAACASP6PRMT5CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10405538-B2 | Platelet storage methods and compositions for same | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2019-09-10 | — | — | US | disclosed |
| US-20180139952-A1 | PLATELET STORAGE METHODS AND COMPOSITIONS FOR SAME | PLATEFUSE, INC. | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180139952-A1 | PLATELET STORAGE METHODS AND COMPOSITIONS FOR SAME | RHOA, ARHGDIB, ARHGDIA | CDC42 11/4885GAA 2228/4885CASP6 3719/4885 |
| US-10405538-B2 | Platelet storage methods and compositions for same | RHOA, ARHGDIB, ARHGDIA | CDC42 11/4885GAA 2228/4885CASP6 3719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.