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ARHGDIA

Rho GDP-dissociation inhibitor 1 · P52565 · ARHGDIA on Sugi Atlas →

434 patent compounds predicted against ARHGDIA, 314 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL1974051 SCHEMBL1974051 1.00 6/20
SCHEMBL5415148 SCHEMBL5415148 0.81 6/20
SCHEMBL1971758 SCHEMBL1971758 0.77 5/20
SCHEMBL5409094 SCHEMBL5409094 0.76 5/20
SCHEMBL1975219 SCHEMBL1975219 0.62 5/20
SCHEMBL5412871 SCHEMBL5412871 0.53 5/20
SCHEMBL1974016 SCHEMBL1974016 1.00 4/20
SCHEMBL1974291 SCHEMBL1974291 1.00 4/20
SCHEMBL1974858 SCHEMBL1974858 1.00 4/20
SCHEMBL1975114 SCHEMBL1975114 0.80 4/20
SCHEMBL12592335 SCHEMBL12592335 0.76 4/20
SCHEMBL5412656 SCHEMBL5412656 0.73 4/20
SCHEMBL5419608 SCHEMBL5419608 0.71 4/20
SCHEMBL5404336 SCHEMBL5404336 0.70 4/20
SCHEMBL5423856 SCHEMBL5423856 0.70 4/20
SCHEMBL5409461 SCHEMBL5409461 0.70 4/20
SCHEMBL5404303 SCHEMBL5404303 0.70 4/20
SCHEMBL5413166 SCHEMBL5413166 0.70 4/20
SCHEMBL5423824 SCHEMBL5423824 0.70 4/20
Hydrochloric Acid Hydrochloric Acid (SCHEMBL5404775) 0.69 4/20

Clinical trials — most relevant to ARHGDIA by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Ketamine Treatment Effects on Synaptic Plasticity in Depression PHASE4COMPLETED
CB-PRP in Retinitis Pigmentosa and Dry Age-related Macular Degeneration PHASE3COMPLETED
Simvastatin + Cetuximab/Irinotecan in K-ras Mutant Colorectal Cancer (CRC) PHASE2COMPLETED
Study of Sorafenib and Docetaxel in Metastatic Prostate Cancer PHASE2COMPLETED
A Multicenter Study of NAP (AL-108) in Schizophrenia PHASE2COMPLETED
NEO100 and High-Grade Meningioma PHASE2RECRUITING
FAK Inhibitor in Patients With Advanced Solid Tumors PHASE1NOT_YET_RECRUITING
Expression and Function of the Renin-Angiotensin System in the Esophagus EARLY_PHASE1COMPLETED
ADRB3, ROCK2 and GEF Levels in Overactive Bladder Patients nanCOMPLETED
Study of the Pathophysiological Mechanisms Involved in Bleeding Events nanCOMPLETED
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Prospective Validation of a DNA Damage Repair-Hippo Pathway Signature in Patients With Advanced Gastric Cancer nanUNKNOWN
Transcranial Magnetic Stimulation (TMS) Studies of Dystonia nanCOMPLETED
Investigating Phenotypic, Epigenetic, and NeuroGenetic Traits in Rare and Ultra-rare Neurodevelopmental Disorders (Project PENGUIN) nanRECRUITING
Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma nanRECRUITING
Speech and Short-term Memory Functions in Dyslexia: a Combined MEG and EEG Study nanUNKNOWN
Thrombin Regulated Platelet Activation nanCOMPLETED
Neurophysiological Markers in Patients With Craniofacial Dystonia and Their Relatives nanCOMPLETED
Genetic Study of Patients With Primary Ciliary Dyskinesia nanCOMPLETED
Gene Analysis of Parkinson's Disease nanCOMPLETED
Rostock International Parkinson's Disease Study (ROPAD) nanCOMPLETED
Prospective Genetic Study in Patients With Ovarian Insufficiency nanUNKNOWN
Research and Characterization of New Genes Involved in Intellectual Disability nanCOMPLETED
A Study on Risk Mutations of Vulnerability Genes of Schizophrenia nanUNKNOWN
Identification of an Asthma Susceptibility Gene on 3P nanCOMPLETED
Role of Polymorphisms in the IL-1 Gene Cluster nanCOMPLETED
Consortium On Risk for Early-onset Parkinson's Disease (CORE PD) nanCOMPLETED
Parkinson's Families Project nanRECRUITING
Family Myopia Study nanCOMPLETED
Implication of Long Non-coding RNA CCDC144NL-AS1/Micro RNA-143-3p Axis Expression Level as Novel Signature in Colorectal Cancer nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a ARHGDIA binder may also engage these)

ProteinNameSimilarity
Q5XI73 — 1.000 Q5XI73 →
Q99PT1 — 1.000 Q99PT1 →
Q4R4J0 — 1.000 Q4R4J0 →
P19803 — 0.997 P19803 →
Q5R5F8 — 0.946 Q5R5F8 →
Q66H80 — 0.946 Q66H80 →
Q9NVE7 — 0.946 Q9NVE7 →
ARCN1 Coatomer subunit delta 0.945 landscape →
Q4R4U1 — 0.945 Q4R4U1 →
Q5XJY5 — 0.944 Q5XJY5 →
Q5RA77 — 0.943 Q5RA77 →
P53619 — 0.943 P53619 →
P38024 — 0.942 P38024 →
AP2A2 AP-2 complex subunit alpha-2 0.942 landscape →
Q5ZL57 — 0.941 Q5ZL57 →
Q6GPR5 — 0.940 Q6GPR5 →
Q9ERA0 — 0.940 Q9ERA0 →
O88545 — 0.940 O88545 →
Q9BPX6 — 0.940 Q9BPX6 →
Q3T178 — 0.939 Q3T178 →
AP2A1 AP-2 complex subunit alpha-1 0.939 landscape →
GPS1 COP9 signalosome complex subunit 1 0.939 landscape →
Q923S8 — 0.939 Q923S8 →
Q0VCL3 — 0.938 Q0VCL3 →
Q9D1C8 — 0.938 Q9D1C8 →
Q5M887 — 0.938 Q5M887 →
P18484 — 0.938 P18484 →
P17427 — 0.938 P17427 →
Q0VCK5 — 0.938 Q0VCK5 →
VPS28 Vacuolar protein sorting-associated protein 28 homolog 0.937 landscape →