Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20181373 | 1.00 | TRPA1 (0.41) | TRPA1TRPV1 | |
| SCHEMBL20181403 | 0.69 | — | — | |
| SCHEMBL20181407 | 0.69 | — | — | |
| SCHEMBL25333337 | 0.69 | — | — | |
| SCHEMBL20181169 | 0.65 | — | — | |
| Lithium Ion SCHEMBL9824424 | 0.62 | TRPA1 (0.41) | TRPA1TRPV1 | |
| SCHEMBL22811397 | 0.61 | — | — | |
| SCHEMBL5724792 | 0.60 | MIF (0.41) | TRPA1TRPV1 | |
| SCHEMBL7001944 | 0.60 | TRPA1 (0.40) | TRPA1TRPV1 | |
| SCHEMBL5724796 | 0.60 | MIF (0.41) | TRPA1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541803-B1 | TRIAZOLE PYRIDYL COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR | AMGEN INC (US) | 2020-12-23 | — | — | EP | disclosed |
| WO-2018093580-A1 | TRIAZOLE PYRIDYL COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR | AMGEN INC. (US) | 2018-05-24 | — | — | WO | disclosed |