Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | SORD | Q00796 | 2/20 | 0.34 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24258924 | 0.85 | KCNH2 (0.35) | RECQLFFAR1SORDKCNH2 | |
| SCHEMBL15577831 | 0.83 | — | — | |
| SCHEMBL2013407 | 0.79 | FFAR1 (0.32) | FFAR1RPS6KA5KCNH2 | |
| SCHEMBL27621059 | 0.79 | FFAR1 (0.32) | FFAR1RPS6KA5KCNH2 | |
| SCHEMBL4263566 | 0.79 | HRH1 (0.45) | FFAR1 | |
| SCHEMBL4273110 | 0.77 | SORD (0.42) | SORD | |
| SCHEMBL16178953 | 0.76 | KCNH2 (0.46) | KCNH2 | |
| SCHEMBL6820237 | 0.76 | CD274 (0.36) | TRPV3 | |
| SCHEMBL27413913 | 0.76 | KDM4E (0.35) | FFAR1 | |
| SCHEMBL501903 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659020-A | Imidazo [1,2-b ] pyridazine derivative, and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-03-08 | — | — | CN | disclosed |
| WO-2020081999-A1 | ANDROGEN RECEPTOR MODULATORS AND METHODS FOR THEIR USE | ESSA PHARMA, INC. (CA) | 2020-04-23 | — | — | WO | disclosed |
| EP-2863914-A1 | PYRAZOLYL DERIVATIVES AS SYK INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2015-04-29 | — | — | EP | disclosed |
| WO-2013192125-A1 | PYRAZOLYL DERIVATIVES AS SYK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2013-12-27 | — | — | WO | disclosed |
| EP-2513098-A1 | AMINOPYRIMIDINES AS SYK INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011075515-A1 | AMINOPYRIMIDINES AS SYK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2011-06-23 | — | — | WO | disclosed |
| WO-2011075517-A1 | AMINOPYRIMIDINES AS SYK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2011-06-23 | — | — | WO | disclosed |