Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | VSIR | Q9H7M9 | 4/20 | 0.36 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981616 | 0.83 | FERMT2 (0.38) | CHRM2 | |
| SCHEMBL12845332 | 0.76 | CYP1A2 (0.43) | CD274PDCD1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL2018150 | 0.76 | RECQL (0.35) | TRPV3 | |
| SCHEMBL17621392 | 0.76 | TRPV3 (0.33) | TRPV3 | |
| SCHEMBL15577831 | 0.75 | — | — | |
| SCHEMBL7653614 | 0.74 | CXCR4 (0.47) | CD274PDCD1VSIRPDCD1LG2 | |
| SCHEMBL17607299 | 0.72 | POLB (0.41) | KMT2AALDH1A1MEN1 | |
| SCHEMBL4474314 | 0.72 | VSIR (0.60) | VSIR | |
| SCHEMBL23255071 | 0.71 | KCNH3 (0.41) | CD274PDCD1VSIRCHRM2ALDH1A1 | |
| SCHEMBL3406133 | 0.71 | NUDT1 (0.51) | KMT2ACYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074287-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-09-02 | — | — | WO | disclosed |