Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | BTN3A1 | O00481 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 8/20 | 0.37 |
| ▸ | METAP1 | P53582 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28273778 | 1.00 | MGAM (0.39) | MGAMGAASIMGAM2BTN3A1 | |
| SCHEMBL21343018 | 0.88 | ALDH1A1 (0.40) | MGAMGAASIMGAM2BTN3A1 | |
| SCHEMBL27494852 | 0.88 | MGAM (0.39) | MGAMGAASIMGAM2BTN3A1 | |
| SCHEMBL12746431 | 0.86 | BTN3A1 (0.39) | MGAMGAASIMGAM2BTN3A1 | |
| SCHEMBL19225305 | 0.83 | MGAM (0.39) | MGAMGAASIMGAM2BTN3A1 | |
| SCHEMBL12746435 | 0.83 | MGAM (0.39) | MGAMGAASIMGAM2BTN3A1 | |
| SCHEMBL13633863 | 0.83 | MGAM (0.39) | MGAMGAASIMGAM2BTN3A1 | |
| SCHEMBL22300379 | 0.82 | BTN3A1 (0.39) | MGAMGAASIMGAM2BTN3A1 | |
| SCHEMBL20144184 | 0.82 | ALDH1A1 (0.41) | MGAMGAASIMGAM2BTN3A1 | |
| SCHEMBL12176868 | 0.81 | BTN3A1 (0.36) | MGAMGAASIMGAM2BTN3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109305990-B | Phosphoric acid derivative, preparation method and application | 四川海思科制药有限公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-109305989-B | Phosphamide derivative and preparation method and application thereof | 四川海思科制药有限公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-110938094-A | Preparation method and application of thyroid hormone receptor β subtype agonist derivative | 四川海思科制药有限公司 | 2020-03-31 | — | — | CN | disclosed |
| US-20190276481-A1 | Liver Prodrugs of Mitochondrial Proton Ionophores | NEUROVIVE PHARMACEUTICAL AB (SE) | 2019-09-12 | — | — | US | disclosed |
| CN-109305989-A | A kind of phosphinylidyne amine derivative and preparation method and purposes | 四川海思科制药有限公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-109305990-A | A kind of phosphoric acid derivatives and preparation method and purposes | 四川海思科制药有限公司 | 2019-02-05 | — | — | CN | disclosed |
| WO-2018091633-A1 | LIVER PRODRUGS OF MITOCHONDRIAL PROTON IONOPHORES | NEUROVIVE PHARMACEUTICAL AB (SE) | 2018-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190276481-A1 | Liver Prodrugs of Mitochondrial Proton Ionophores | GLS2, CYP27A1, SLC25A21 | MGAM 1707/4885GAA 615/4885SI 490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.