Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM5 | Q9NZQ8 | 17/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.34 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22898336 | 1.00 | TRPM5 (0.34) | TRPM5TRPA1TRPM4CNR2 | |
| SCHEMBL22898318 | 0.98 | TRPM5 (0.35) | TRPM5TRPA1TRPM4 | |
| SCHEMBL19386714 | 0.78 | TRPM5 (0.35) | TRPM5TRPA1TRPM4 | |
| SCHEMBL9917320 | 0.76 | TRPM5 (0.39) | TRPM5TRPA1TRPM4 | |
| SCHEMBL22066242 | 0.75 | SMPD1 (0.32) | — | |
| SCHEMBL21720251 | 0.74 | SMPD1 (0.31) | — | |
| SCHEMBL18994862 | 0.72 | HTT (0.39) | CNR2 | |
| SCHEMBL21185908 | 0.71 | PLA2G4A (0.33) | CNR2 | |
| SCHEMBL22898337 | 0.71 | HTT (0.38) | CNR2 | |
| SCHEMBL22898339 | 0.70 | HTT (0.37) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11008339-B2 | Substituted pyrazole compounds containing pyrimidine and preparation method and use thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2021-05-18 | — | — | US | disclosed |
| US-20180141961-A1 | Substituted Pyrazole Compounds Containing Pyrimidine and Preparation Method and Use Thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141961-A1 | Substituted Pyrazole Compounds Containing Pyrimidine and Preparation Method and Use Thereof | APRT, GART, PNP | TRPM5 2492/4885TRPA1 531/4885TRPM4 3349/4885 |
| US-11008339-B2 | Substituted pyrazole compounds containing pyrimidine and preparation method and use thereof | APRT, GART, PNP | TRPM5 2492/4885TRPA1 531/4885TRPM4 3349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.