Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30037220 | 0.84 | ADK (0.41) | ADKMEN1NR2F2KMT2ASRC | |
| SCHEMBL20162965 | 0.84 | ADK (0.41) | ADKMEN1NR2F2KMT2ASRC | |
| SCHEMBL25611698 | 0.83 | ADK (0.45) | ADKMEN1NR2F2KMT2ASRC | |
| SCHEMBL20181879 | 0.82 | RET (0.41) | ADKSRC | |
| SCHEMBL20182230 | 0.82 | ADK (0.38) | ADKMEN1NR2F2KMT2A | |
| SCHEMBL20181850 | 0.80 | ADK (0.39) | ADKMEN1NR2F2KMT2A | |
| SCHEMBL20181888 | 0.72 | ADK (0.44) | ADKMEN1NR2F2KMT2ASRC | |
| SCHEMBL6935719 | 0.71 | ADK (0.48) | ADKMEN1NR2F2KMT2ASRC | |
| SCHEMBL30038177 | 0.70 | DYRK3 (0.44) | ADKSRC | |
| SCHEMBL20162723 | 0.70 | DYRK3 (0.44) | ADKSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018094137-A1 | PYRROLOPYRIMIDINES AS CFTR POTENTIATORS | CYSTIC FIBROSIS FOUNDATION THERAPEUTICS INC. (US) | 2018-05-24 | — | — | WO | disclosed |