Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20162624 | 0.85 | ADK (0.39) | ADK | |
| SCHEMBL20182185 | 0.85 | RET (0.41) | ADK | |
| SCHEMBL20182341 | 0.80 | ADK (0.40) | ADKMEN1NR2F2KMT2A | |
| SCHEMBL20182230 | 0.76 | ADK (0.38) | ADKMEN1NR2F2KMT2A | |
| SCHEMBL25611698 | 0.74 | ADK (0.45) | ADKMEN1NR2F2KMT2A | |
| SCHEMBL20163009 | 0.72 | MTOR (0.42) | ADK | |
| SCHEMBL20351622 | 0.69 | ADK (0.56) | ADK | |
| SCHEMBL20181888 | 0.67 | ADK (0.44) | ADKMEN1NR2F2KMT2A | |
| SCHEMBL19264034 | 0.67 | ADK (0.53) | ADK | |
| SCHEMBL20351756 | 0.67 | ADK (0.53) | ADKMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018094137-A1 | PYRROLOPYRIMIDINES AS CFTR POTENTIATORS | CYSTIC FIBROSIS FOUNDATION THERAPEUTICS INC. (US) | 2018-05-24 | — | — | WO | disclosed |