Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20182410 | 0.86 | MAPT (0.48) | MAPTTP53KDM4EALOX15HPGD | |
| SCHEMBL7927301 | 0.83 | ALDH1A1 (0.57) | MAPTKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL20168837 | 0.80 | MAPT (0.49) | MAPTTP53KDM4EALOX15HPGD | |
| SCHEMBL18570397 | 0.78 | APP (0.49) | MAPTKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL22090726 | 0.76 | ALDH1A1 (0.45) | MAPTKDM4EALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL4232553 | 0.76 | PTGDR2 (0.61) | MAPTTSHRTDP1PTGDR2 | |
| SCHEMBL30933896 | 0.76 | ALDH1A1 (0.49) | MAPTKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL20798229 | 0.74 | MAPT (0.74) | MAPTTP53KDM4EALOX15HPGD | |
| SCHEMBL3329518 | 0.73 | HPGD (0.51) | MAPTKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL28916081 | 0.73 | SMN1; SMN2 (0.44) | MAPTTP53KDM4EALOX15HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093949-A1 | MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-05-24 | — | — | WO | disclosed |