SCHEMBL20182418

SCHEMBL20182418

CC(C)(C)OC(=O)CCCOc1cc(Cl)cc(CN2CCCC23CCN(C(=O)OC(C(F)(F)F)C(F)(F)F)CC3)c1

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 6/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29446979 1.00 MGLL (0.74) MGLL
SCHEMBL29494560 0.90 MGLL (0.79) MGLL
SCHEMBL20168654 0.90 MGLL (0.79) MGLL
SCHEMBL25802719 0.85 MGLL (1.00) MGLL
SCHEMBL20182657 0.84 MGLL (0.81) MGLL
SCHEMBL29417732 0.81 MGLL (0.60) MGLL
SCHEMBL19582409 0.81 MGLL (0.60) MGLL
SCHEMBL25802784 0.80 MGLL (0.70) MGLL
SCHEMBL20168832 0.79 MGLL (0.81) MGLL
SCHEMBL25802667 0.79 MGLL (0.85) MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3541820-B1 MAGL INHIBITORS H LUNDBECK AS (DK) 2023-07-05 EP disclosed
EP-3541820-B1 MAGL INHIBITORS H LUNDBECK AS (DK) 2023-07-05 EP disclosed
US-11691975-B2 MAGL inhibitors H. LUNDBECKA/S (DK) 2023-07-04 US disclosed
US-11691975-B2 MAGL inhibitors H. LUNDBECKA/S (DK) 2023-07-04 US disclosed
US-20220135563-A1 MAGL INHIBITORS H. LUNDBECK A/S (DK) 2022-05-05 US disclosed
CN-110267962-B MAGL inhibitors H.隆德贝克有限公司 2022-04-01 CN disclosed
US-11059822-B2 MAGL inhibitors H. LUNDBECK A/S (DK) 2021-07-13 US disclosed
US-11059822-B2 MAGL inhibitors H. LUNDBECK A/S (DK) 2021-07-13 US disclosed
US-20200291023-A1 MAGL INHIBITORS H. LUNDBECK A/S (DK) 2020-09-17 US disclosed
US-20200291023-A1 MAGL INHIBITORS H. LUNDBECK A/S (DK) 2020-09-17 US disclosed
WO-2018093949-A1 MAGL INHIBITORS ABIDE THERAPEUTICS, INC. (US) 2018-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11059822-B2 MAGL inhibitors MAG, MAGI3, MGLL MGLL 3/4885
US-20220135563-A1 MAGL INHIBITORS MAG, MAGI3, MGLL MGLL 3/4885
US-20200291023-A1 MAGL INHIBITORS MAG, MAGI3, MGLL MGLL 3/4885
US-11691975-B2 MAGL inhibitors MAG, MAGI3, MGLL MGLL 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.