SCHEMBL29446979

SCHEMBL29446979

CC(C)(C)OC(=O)CCCOc1cc(Cl)cc(CN2CCCC23CCN(C(=O)OC(C(F)(F)F)C(F)(F)F)CC3)c1

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 6/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20182418 1.00 MGLL (0.74) MGLL
SCHEMBL29494560 0.90 MGLL (0.79) MGLL
SCHEMBL20168654 0.90 MGLL (0.79) MGLL
SCHEMBL25802719 0.85 MGLL (1.00) MGLL
SCHEMBL20182657 0.84 MGLL (0.81) MGLL
SCHEMBL29417732 0.81 MGLL (0.60) MGLL
SCHEMBL19582409 0.81 MGLL (0.60) MGLL
SCHEMBL25802784 0.80 MGLL (0.70) MGLL
SCHEMBL20168832 0.79 MGLL (0.81) MGLL
SCHEMBL25802667 0.79 MGLL (0.85) MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110267962-B MAGL inhibitors H.隆德贝克有限公司 2022-04-01 CN disclosed