SCHEMBL20182548

SCHEMBL20182548

CCCNC(=O)C/C(C(=O)NCCNC(=O)OC(C)(C)C)=C(/N)NC

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
TDP1 Q9NUW8 1/20 0.38
MEN1 O00255 1/20 0.37
GAA P10253 1/20 0.37
KMT2A Q03164 1/20 0.37
EPHX1 P07099 1/20 0.36
CA1 P00915 10/20 0.34
CA2 P00918 10/20 0.34
CA12 O43570 7/20 0.33
CA9 Q16790 7/20 0.33
CTSK P43235 2/20 0.33
MALT1 Q9UDY8 1/20 0.32
BCHE P06276 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21478060 0.77 TDP1 (0.43) MAOAMAOBTDP1MEN1GAA
SCHEMBL61208 0.75 TDP1 (0.60) MAOAMAOBTDP1MEN1GAA
SCHEMBL22871761 0.74 TDP1 (0.40) MAOAMAOBTDP1MEN1GAA
Hydrochloric Acid SCHEMBL28763000 0.73 TDP1 (0.58) MAOAMAOBTDP1MEN1GAA
Bromide SCHEMBL28241790 0.73 TDP1 (0.58) MAOAMAOBTDP1MEN1GAA
Ammonia Solution, Strong SCHEMBL6807094 0.73 TDP1 (0.58) MAOAMAOBTDP1MEN1GAA
Hydrochloric Acid SCHEMBL27646037 0.73 TDP1 (0.58) MAOAMAOBTDP1MEN1GAA
SCHEMBL15244383 0.73 TDP1 (0.50) MAOAMAOBTDP1MEN1GAA
SCHEMBL20182557 0.72 MEN1 (0.45) MAOAMAOBTDP1MEN1GAA
Hydrochloric Acid SCHEMBL5973455 0.72 TDP1 (0.56) MAOAMAOBTDP1MEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018091467-A2 A SIMULTANEOUSLY ANTIMICROBIAL AND PROTEIN-REPELLENT POLYZWITTERION ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) 2018-05-24 WO disclosed