Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | PARG | Q86W56 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18256041 | 0.85 | TRPA1 (0.44) | TRPA1KMT2ALMNACYP1A2NFKB1 | |
| SCHEMBL18256106 | 0.85 | TRPA1 (0.44) | TRPA1KMT2ALMNACYP1A2NFKB1 | |
| SCHEMBL18255888 | 0.85 | TRPA1 (0.46) | TRPA1KMT2ALMNACYP1A2NFKB1 | |
| SCHEMBL18256053 | 0.84 | TRPA1 (0.44) | TRPA1KMT2ALMNACYP1A2NFKB1 | |
| SCHEMBL18255892 | 0.82 | PDE4A (0.50) | TRPA1LMNACYP1A2NFKB1ACHE | |
| SCHEMBL18255906 | 0.81 | PDE4A (0.60) | TRPA1LMNACYP1A2NFKB1ACHE | |
| SCHEMBL18256094 | 0.81 | TRPA1 (0.44) | TRPA1KMT2ALMNACYP1A2NFKB1 | |
| SCHEMBL18255907 | 0.80 | PDE4A (0.53) | TRPA1LMNACYP1A2NFKB1ACHE | |
| SCHEMBL18255884 | 0.80 | LMNA (0.45) | TRPA1LMNACYP1A2NFKB1ACHE | |
| SCHEMBL20182456 | 0.79 | TRPA1 (0.42) | TRPA1KMT2ALMNAPOLBHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180140607-A1 | HYDROXYL PURINE COMPOUNDS AND USE THEREOF | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180140607-A1 | HYDROXYL PURINE COMPOUNDS AND USE THEREOF | PNP, PDE7A, PDE2A | TRPA1 2926/4885KMT2A 3576/4885LMNA 2317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.